Product Description: D-PheTrAP is a bisubstrate analog inhibitor of 1-Deoxy-d-xylulose 5-phosphate synthase (DXPS). D-PheTrAP inhibits Escherichia coli DXPS (EcDXPS) and Pseudomonas aeruginosa DXPS (PaDXPS) with IC50 values of 0.52 μM, 2.1 μM, 2.4 μM, and 1.7 μM for wild-type (WT) EcDXPS, EcA426E, WT PaDXPS, and PaE431A, respectively[1].
Formula: C15H18N3O6P
References: [1]Henriquez S, et al. Bisubstrate Analog Inhibitors of DXP Synthase Show Species Specificity. Biochemistry. 2025 Jan 21;64(2):432-447.
CAS Number: 2241298-26-8
Molecular Weight: 367.29
Research Area: Infection
Target: Bacterial