Product Description: Δ7(Z)-C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7(Z)-C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes[1].
Applications: COVID-19-immunoregulation
Formula: C18H29NO4
References: [1]Chhabra SR, et al. Synthetic analogues of the bacterial signal (quorum sensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulators. J Med Chem. 2003 Jan 2;46(1):97-104.
CAS Number: 482598-46-9
Molecular Weight: 323.43
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Others