dBAZ2

Product Description: dBAZ2 is a first-in-class BAZ2A and BAZ2B PROTAC degrader with DC50 values of 180 nM and 250 nM for BAZ2A and BAZ2B, respectively. (Blue: E3 ligase ligand (VH 101, thiol (HY-47851); Black: linker (HY-168450); pink: target protein ligand (HY-168449))[1].

Applications: Cancer-programmed cell death

Formula: C54H64FN11O5S2

References: [1]Leonardo Palaferri, et al. Discovery of First-in-Class BAZ2A/B and BAZ2B-Selective Degraders. ACS Med Chem Lett. January 7, 2025.

Molecular Weight: 1030.29

Research Area: Cancer

Target: Epigenetic Reader Domain;PROTACs

• SKU: MEXHY-168448-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168448-0
• Package Unit: Get quote
• Quantity Unit: STK