DBM 1285 (dihydrochloride), CAS 1782532-29-9

Product Description: DBM 1285 dihydrochloride is an orally active TNF-α production inhibitor with anti-inflammatory effects. DBM 1285 dihydrochloride inhibits Lipopolysaccharide (LPS)-induced TNF-α secretion in various cells of macrophage/monocyte lineage[1].

Applications: COVID-19-immunoregulation

Formula: C21H24Cl2FN5S

References: [1]Jong Soon Kang, et al. DBM1285 suppresses tumor necrosis factor alpha production by blocking p38 mitogen-activated protein kinase/mitogen-activated protein kinase-activated protein kinase 2 signaling pathway. J Pharmacol Exp Ther. 2010 Aug;334(2):657-64.

CAS Number: 1782532-29-9

Molecular Weight: 468.42

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: TNF Receptor

• SKU: MEXHY-110343-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110343-10
• Package Unit: 10 mg
• Quantity Unit: STK