DCEM1, CAS 878949-21-4

Product Description: DCEM1 binds to heat shock protein 60 (HSP60) and inhibits the interaction of HSP60 with ClpP, thereby blocking the mitochondrial unfolded protein response. DCEM1 inhibits β-catenin expression and ATP production in PC-3 and TKO cells. DCEM1 can be used in prostate cancer research[1][2].

Formula: C22H23N3O2S

References: [1]Dhyan C, et al. Methods for disrupting mitochondrial unfolded protein response. WO2022103897. WIPO (PCT). 2021-11-10./[2]Woytash JA, et al. Mitochondrial unfolded protein response-dependent β-catenin signaling promotes neuroendocrine prostate cancer. Oncogene. 2025 Apr;44(12):820-834.

CAS Number: 878949-21-4

Molecular Weight: 393.50

Research Area: Cancer

Target: HSP;β-catenin

• SKU: MEXHY-171616-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171616-50
• Package Unit: 50 mg
• Quantity Unit: STK