DM-NOFD, CAS 865488-53-5

Product Description: DM-NOFD is a cell penetrant, prodrug of NOFD a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF)[1][2].

Formula: C13H15NO5

References: [1]Luczak MW, Krawic C, Zhitkovich A. NAD+ metabolism controls growth inhibition by HIF1 in normoxia and determines differential sensitivity of normal and cancer cells. Cell Cycle. 2021 Sep;20(18):1812-1827./[2]Corner TP, et al. Structure-guided optimisation of N-hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-α. Chem Sci. 2023 Oct 27;14(43):12098-12120.

CAS Number: 865488-53-5

Molecular Weight: 265.26

Research Area: Cancer

Target: HIF/HIF Prolyl-Hydroxylase

• SKU: MEXHY-112068-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112068-0
• Package Unit: Get quote
• Quantity Unit: STK