DNA Gyrase-IN-15

Product Description: DNA Gyrase-IN-15 (Compound 11) is an antimicrobial agent and inhibitor of DHPS and DNA gyrase, with IC50s of 1.73 and 0.07 µM, respectively. DNA Gyrase-IN-15 shows antimicrobial activity against Enterococcus faecalis (MIC of 15.62 µg/mL), Acinetobacter baumannii, Enterobacter species (MIC of 7.81 µg/mL), Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus. DNA Gyrase-IN-15 also shows antibiofilm activity against Enterococcus faecalis[1].

Applications: COVID-19-anti-virus

Formula: C31H26N4O4S2

References: [1]Abd El-Mawgoud HK, et al. Synthesis of tetra-substituted thiophene derivatives as potential Hits combating antibiotic resistant bacteria ESKAPE. Bioorg Chem. 2025 Jan 8;155:108101.

Molecular Weight: 582.69

Research Area: Infection

Target: DNA/RNA Synthesis

• SKU: MEXHY-172109-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172109-0
• Package Unit: Get quote
• Quantity Unit: STK