DNJ-20, CAS 3081926-49-7

Product Description: DNJ-20 is an α-glucosidase inhibitor (IC50: 55.3 μg/mL). DNJ-20 has broad-spectrum anti-SARS-CoV-2 activity. DNJ-20 inhibits the correct processing of viral glycoproteins by interfering with the endoplasmic reticulum-associated glycoprotein folding process (ERQC), thereby blocking the formation and infection of viral particles. DNJ-20 has IC50 values up to 1.49 uM against several SARS-CoV-2 variants, as well as HCoV-229E and HCoV-0C43。DNJ-20 can be used for pan-coronavirus research[1].

Formula: C31H41NO10

References: [1]Liu YY, et al. TCM theory-inspired discovery of DNJ-flavonoid conjugates as broad-spectrum anti-SARS-CoV-2 agents by primarily targeting ER-associated glycoprotein folding process. Eur J Med Chem. 2025 Jun 5;290:117582.

CAS Number: 3081926-49-7

Molecular Weight: 587.66

Research Area: Infection; Inflammation/Immunology

Target: Glycosidase;SARS-CoV

• SKU: MEXHY-173411-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173411-0
• Package Unit: Get quote
• Quantity Unit: STK