Donepezil (Standard), CAS 120014-06-4

Donepezil (Standard), CAS 120014-06-4
SKU
MEXHY-14566R-100
Packaging Unit
100 mg
Manufacturer
MedChemExpress

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Product Description: Donepezil (Standard) is the analytical standard of Donepezil. This product is intended for research and analytical applications. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].

Formula: C24H29NO3

References: [1]Ogura, H., et al., Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol, 2000. 22(8): p. 609-13./[2]Snape, M.F., et al., A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066. Neuropharmacology, 1999. 38(1): p. 181-93./[3]Huang, Z.H., et al., Donepezil protects endothelial cells against hydrogen peroxide-induced cell injury. CNS Neurosci Ther, 2012. 18(2): p. 185-7.

CAS Number: 120014-06-4

Molecular Weight: 379.49

Research Area: Neurological Disease; Cancer

Target: Cholinesterase (ChE);Reference Standards
More Information
SKU MEXHY-14566R-100
Manufacturer MedChemExpress
Manufacturer SKU HY-14566R-100
Package Unit 100 mg
Quantity Unit STK
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