Drofenine (hydrochloride), CAS 548-66-3

Shelf life (days): 1460

Info: An M1 muscarinic receptor antagonist; inhibits carbachol-induced inositol phosphate accumulation in isolated guinea pig cortical slices, which endogenously express M1 muscarinic receptors (pA2 = 8.15); inhibits BChE isolated from human serum (Ki = 3 µM); induces inward currents in whole-cell patch-clamp assays using HEK293 cells overexpressing TRPV3 (EC50 = 205 µM); increases hepatic levels of α-Sma and collagen I in a mouse model of CCl4-induced hepatic fibrosis at 5 mg/kg twice per week

Formulation: A solid

Formal Name: α-cyclohexyl-benzeneacetic acid, 2-(diethylamino)ethyl ester, monohydrochloride

Purity: ≥98%

Formula Markup: C20H31NO2 • HCl

Formula Weight: 353.931

CAS Number: 548-66-3

• SKU: CAY43153-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43153-50
• Package Unit: 50 mg
• Quantity Unit: STK