(E/Z)-3PO, CAS 13309-08-5

Product Description: (E/Z)-3PO is a potent PFKFB3 inhibitor. (E/Z)-3PO can inhibit the glycolysis process, reduce the extracellular acidification rate, and inhibit the capillary tube formation, migration of endothelial cells, and the formation of aortic sprouts, thereby suppressing angiogenesis. (E/Z)-3PO is promising for research of diseases such as cancer, acute lung injury, pulmonary fibrosis, and atherosclerosis[1].

Applications: Cancer-programmed cell death

Formula: C13H10N2O

References: [1]Emini Veseli B, et al. Small molecule 3PO inhibits glycolysis but does not bind to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3). FEBS Lett. 2020 Sep;594(18):3067-3075.

CAS Number: 13309-08-5

Molecular Weight: 210.24

Compound Purity: 99.86

Research Area: Cancer; Cardiovascular Disease

Target: Phosphatase

• SKU: MEXHY-110169-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110169-1
• Package Unit: 1 mg
• Quantity Unit: STK