E3 Ligase Ligand-linker Conjugate 159

Product Description: E3 Ligase Ligand-linker Conjugate 159 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 159 can be used for the synthesis of SMD-3236 (HY-170824), a PRAOTAC that targets the degradation of SMARCA2, exhibiting long-lasting antitumor activity in vivo[1].

Formula: C37H53N7O7S2

References: [1]Yang L, et al. Discovery of SMD-3236: A Potent, Highly Selective and Efficacious SMARCA2 Degrader for the Treatment of SMARC4-Deficient Human Cancers. J Med Chem. 2025 Jan 23;68(2):1155-1178.

Molecular Weight: 771.99

Research Area: Cancer

Target: E3 Ligase Ligand-Linker Conjugates

• SKU: MEXHY-170827-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170827-0
• Package Unit: Get quote
• Quantity Unit: STK