Eliglustat, CAS 491833-29-5

Product Description: Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.

Applications: Metabolism-protein/nucleotide metabolism

Formula: C23H36N2O4

Citations: Cell Death Dis. 2021 Oct 6;12(10):911./EMBO J. 2022 Dec 12;e110553./Nat Commun. 2020 Aug 27;11(1):4279./Nat Commun. 2024 Aug 14;15(1):6970./bioRxiv. 2021 Feb 2./Cancer Discov. 2022 Nov 4;CD-22-0535./Immunity. 2021 Jan 12;54(1):132-150.e9./Int J Biol Macromol. 2024 Dec 2:285:138303./Leiden University. 2022 Jun 15./PLoS One. 2021 Oct 25;16(10):e0247211./Stem Cells Transl Med. 2021 Mar 3.

References: [1]McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-68.

CAS Number: 491833-29-5

Molecular Weight: 404.54

Compound Purity: 99.95

Research Area: Metabolic Disease; Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Glucosylceramide Synthase (GCS)

• SKU: MEXHY-14885-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14885-25
• Package Unit: 25 mg
• Quantity Unit: STK