EMT inhibitor-3, CAS 2930726-89-7

Product Description: EMT inhibitor-3 (compound 11i) is a epithelial-mesenchymal transition (EMT) inhibitor. EMT inhibitor-3 inhibits neuroblastoma SK-N-SH cells with an IC50 of 2.5 μM. EMT inhibitor-3 inhibits SK-N-SH cell proliferation, migration, and invasion. EMT inhibitor-3 increases the Bax/Bcl-2 protein expression ratio, promotes Cytochrome C ( HY-125857) release from mitochondria, and activates caspases 9 and caspases 3, inducing mitochondria-mediated endogenous tumor cell Apoptosis. EMT inhibitor-3 is potential for cancer research[1].

Applications: Cancer-programmed cell death

Formula: C29H21F2N3O4Se

CAS Number: 2930726-89-7

Molecular Weight: 592.45

Research Area: Cancer

Target: Apoptosis;Bcl-2 Family;Caspase;Cytochrome P450

• SKU: MEXHY-170929-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170929-0
• Package Unit: Get quote
• Quantity Unit: STK