EN1441, CAS 2196448-47-0

Product Description: EN1441 is a covalent degrader targeting the androgen receptor (AR) with an EC50 value of 4.2 μM and its truncated variant AR-V7. EN1441 selectively and potently degrades both AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 is promising for research of androgen-independent prostate cancers[1].

Formula: C13H13ClN2O2

References: [1]Zammit CM, et al. Covalent Destabilizing Degrader of AR and AR-V7 in Androgen-Independent Prostate Cancer Cells. bioRxiv [Preprint]. 2025 Feb 16:2025.02.12.637117.

CAS Number: 2196448-47-0

Molecular Weight: 264.71

Compound Purity: 99.67

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Androgen Receptor

• SKU: MEXHY-173626-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173626-50
• Package Unit: 50 mg
• Quantity Unit: STK