Epothilone B (Standard), CAS 152044-54-7

Product Description: Epothilone B (Standard) is the analytical standard of Epothilone B. This product is intended for research and analytical applications. Epothilone B is a microtubule stabilizer with a Ki of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.

Formula: C27H41NO6S

References: [1]Regueiro-Ren A, et al. Synthesis and biological activity of novel epothilone aziridines. Org Lett. 2001 Aug 23;3(17):2693-6./[2]Pagano A, et al. Epothilone B inhibits migration of glioblastoma cells by inducing microtubule catastrophes and affecting EB1 accumulation at microtubule plus ends. Biochem Pharmacol. 2012 Aug 15;84(4):432-43./[3]Oehler C, et al. The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells. Neuro Oncol. 2011 Sep;13(9):1000-10.

CAS Number: 152044-54-7

Molecular Weight: 507.68

Research Area: Cancer; Infection

Target: Antibiotic;Apoptosis;Bacterial;Fungal;Microtubule/Tubulin;Reference Standards

• SKU: MEXHY-17029R-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17029R-50
• Package Unit: 50 mg
• Quantity Unit: STK