ERβ agonist-1, CAS 2412715-30-9

Product Description: ERβ agonist-1 (Compound 8) is a dual-active selective ERβ agonist (EC50: 46.8 nM) and AR antagonist (IC50: 1555 nM). ERβ agonist-1 activates ERβ signaling by binding to ERβ and inhibits AR activity. ERβ agonist-1 retains selective ERβ agonist activity in mouse models and can be used to study prostate cancer[1].

Formula: C25H36O2

References: [1]Bucknam AR, et al. An Estrogen Receptor β Agonist with AR Antagonist Activity from a Modern Asymmetric De Novo Steroid Synthesis. ACS Med Chem Lett. 2025 Mar 27;16(4):631-637.

CAS Number: 2412715-30-9

Molecular Weight: 368.55

Research Area: Cancer

Target: Androgen Receptor;Estrogen Receptor/ERR

• SKU: MEXHY-173474-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173474-0
• Package Unit: Get quote
• Quantity Unit: STK