Product Description: Estrone acetate (Hogival) is an estrogen derivative and an estrogen receptor (ER) activator. It promotes mammary gland development, stimulates pituitary prolactin secretion, and induces the proliferation and activation of lactotrophs (e.g., by reducing prolactin storage granule size while increasing rough endoplasmic reticulum and Golgi apparatus volume density). Estrone acetate holds potential for endocrine research, particularly in studying estrogen's effects on pituitary function, prolactin regulation, and mammary tumor models[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C20H24O3
References: [1]McComb DJ, et al. Enhanced responsiveness of lactotrophs in ectopic pituitaries to bromocryptine and estrone acetate. Acta Anat (Basel). 1981;110(2):113-20.
CAS Number: 901-93-9
Molecular Weight: 312.40
Research Area: Endocrinology
Target: Estrogen Receptor/ERR