Product Description: Eteplirsen (AVI 4658) sodium is a synthetic antisense oligonucleotide that induces dystrophin production. Eteplirsen (AVI 4658) sodium promotes exon 51 skipping in Duchenne muscular dystrophy patients and can be used in Duchenne muscular dystrophy research[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C364H539N177Na30O122P30
References: [1]Kenji Rowel Q Lim, et al. Eteplirsen in the treatment of Duchenne muscular dystrophy. Drug Des Devel Ther. 2017 Feb 28;11:533-545./[2]Charleston J, et al. Long-term treatment with eteplirsen promotes exon 51 skipping and novel dystrophin protein production in duchenne muscular dystrophy patients[J]. Neuromuscular Disorders, 2016, 26: S153.
Molecular Weight: 10965.17
Compound Purity: 91.16
Research Area: Metabolic Disease
Solubility: 10 mM in H2O
Target: Others