ETP-45835, CAS 794510-70-6

Product Description: ETP-45835 is slective and potent MNK inhibitor with IC50s of 575 nM and 646 nM for MNK1 and MNK2, respectively. ETP-45835 shows little activity against 24 other kinases. ETP-45835 inhibits eIF4E Ser209 phosphorylation in cells, and has anticancer effects[1].

Formula: C13H16N4

References: [1]Julen Oyarzabal, et al. Discovery of mitogen-activated protein kinase-interacting kinase 1 inhibitors by a comprehensive fragment-oriented virtual screening approach. J Med Chem. 2010 Sep 23;53(18):6618-28.

CAS Number: 794510-70-6

Molecular Weight: 228.29

Research Area: Cancer

Target: MNK

• SKU: MEXHY-W846144-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W846144-0
• Package Unit: Get quote
• Quantity Unit: STK