Factor D inhibitor 6, CAS 1386455-51-1

Product Description: Factor D inhibitor 6 is a potent, highly selective and orally active factor D (FD) inhibitor with an IC50 of 30 nM and a Kd of 6 nM. Factor D inhibitor 6 is inactive against factor B, lassical and lectin complement-pathway activation, and a broad assay panel of receptors, ion channels, kinases and proteases[1].

Applications: COVID-19-immunoregulation

Formula: C23H22ClFN6O3

References: [1]Jürgen Maibaum, et al. Small-molecule Factor D Inhibitors Targeting the Alternative Complement Pathway. Nat Chem Biol. 2016 Dec;12(12):1105-1110.

CAS Number: 1386455-51-1

Molecular Weight: 484.91

Compound Purity: 99.45

Research Area: Inflammation/Immunology

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Complement System

• SKU: MEXHY-122700-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-122700-1
• Package Unit: 1 mg
• Quantity Unit: STK