Flecainide (hydrochloride), CAS 57415-44-8

Product Description: Flecainide hydrochloride is an orally active antiarrhythmic agent. Flecainide hydrochloride can block sodium channels and inhibit calcium ion release mediated by the cardiac ryanodine receptor (RyR2). Flecainide hydrochloride can be used in the research of diseases such as catecholaminergic polymorphic ventricular tachycardia (CPVT)[1][2][3].

Applications: Neuroscience-Neuromodulation

Formula: C17H21ClF6N2O3

References: [1]Kuroda Y, et al. Flecainide ameliorates arrhythmogenicity through NCX flux in Andersen-Tawil syndrome-iPS cell-derived cardiomyocytes. Biochem Biophys Rep. 2017 Jan 11;9:245-256./[2]Watanabe H, et al. Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans. Nat Med. 2009 Apr;15(4):380-3.

CAS Number: 57415-44-8

Molecular Weight: 450.80

Compound Purity: 98.02

Research Area: Cardiovascular Disease

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Potassium Channel;Sodium Channel

• SKU: MEXHY-W010950A-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W010950A-25
• Package Unit: 25 mg
• Quantity Unit: STK