Product Description: Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research[1][2].
Applications: Cancer-programmed cell death
Formula: C20H23N7O6
References: [1]Costantini CL, et al. Resection of hepatic metastasis after 5-fluorouracil and cofactor for colon cancer. Hepatogastroenterology. 2009;56(91-92):645-649./[2]Carlsson G, et al. 5-fluorouracil (5-FU) and 5,10-methylene tetrahydrofolate (5,10-CH2FH4) as adjuvant therapy in an experimental rodent colon carcinoma model. Anticancer Res. 1997;17(5A):3671-3674./[3]Botto LD, et al. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol. 2000;151(9):862-877.
CAS Number: 3432-99-3
Molecular Weight: 457.44
Compound Purity: 94.87
Research Area: Cancer
Solubility: H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Endogenous Metabolite
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