Product Description: Fosdevirine (GSK2248761) is is a potent, selective, non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1) replication with low nanomolar activity in vitro. Fosdevirine shows good activity against a broad range of HIV-1 strains, including efavirenz (HY-10572)-resistant clinical isolates[1].
Applications: COVID-19-anti-virus
Formula: C20H17ClN3O3P
References: [1]Castellino S, et al. Central nervous system disposition and metabolism of Fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase inhibitor: an LC-MS and Matrix-assisted laser desorption/ionization imaging MS investigation into central nervous system toxicity. Chem Res Toxicol. 2013 Feb 18;26(2):241-51.
CAS Number: 1018450-26-4
Molecular Weight: 413.79
Compound Purity: 98.96
Research Area: Infection
Solubility: 10 mM in DMSO
Target: HIV;Reverse Transcriptase
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