GABAA receptor modulator-3

Product Description: GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). GABAA receptor modulator-3 inhibits α1β3γ2 GABAAR at peak and steady state currents with IC50s of 671 and 64 μM, respectively[1].

Formula: C18H22O2

References: [1]Xu Y, et al. Design, Synthesis, and Pharmacological Evaluation of Nonsteroidal Tricyclic Ligands as Modulators of GABAA Receptors. J Med Chem. 2025 Feb 13;68(3):3795-3813.

Molecular Weight: 270.37

Research Area: Neurological Disease

Target: GABA Receptor

• SKU: MEXHY-170903-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170903-0
• Package Unit: Get quote
• Quantity Unit: STK