GAK inhibitor 2, CAS 2396706-31-1

Product Description: GAK inhibitor 2 (Compound 14g) is a potent cyclin G-associated kinase (GAK) inhibitor with an IC50 of 0.024 μM. GAK inhibitor 2 shows antiviral activity with an EC50 of 1.049 μM against dengue virus (DENV)[1].

Applications: COVID-19-anti-virus

Formula: C20H23N3O3S

References: [1]Martinez-Gualda B, et al. Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase. Bioorg Med Chem. 2020 Jan 1;28(1):115188.

CAS Number: 2396706-31-1

Molecular Weight: 385.48

Compound Purity: 98.58

Research Area: Infection

Solubility: DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Antibiotic;Dengue Virus;Flavivirus

• SKU: MEXHY-147761-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-147761-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK