Gardiquimod (hydrochloride), CAS 2956183-81-4

Product Description: Gardiquimod (hydrochloride) is an imidazoline TLR7/8 agonist. Gardiquimod (hydrochloride) inhibits HIV-1 infection of macrophages and activates peripheral blood mononuclear cells (PBMCs). Gardiquimod (hydrochloride) specifically activates TLR7 at concentrations below 10 μM[1][2].

Formula: C17H24ClN5O

References: [1]Buitendijk M, et al. Gardiquimod: a Toll-like receptor-7 agonist that inhibits HIV type 1 infection of human macrophages and activated T cells. AIDS Res Hum Retroviruses. 2013 Jun;29(6):907-18./[2]Zhou Z, et al. TLR7/8 agonists promote NK-DC cross-talk to enhance NK cell anti-tumor effects in hepatocellular carcinoma. Cancer Lett. 2015 Dec 28;369(2):298-306.

CAS Number: 2956183-81-4

Molecular Weight: 349.86

Research Area: Cancer; Infection

Target: HIV;Toll-like Receptor (TLR)

• SKU: MEXHY-103697B-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-103697B-0
• Package Unit: Get quote
• Quantity Unit: STK