GDC-0134, CAS 1637394-01-4

Product Description: GDC-0134 is a potent, selective, orally active, brain-penetrant dual leucine zipper kinase (DLK) inhibitor. GDC-0134 blocks DLK activity in cellular assays and in animal models of neuronal injury. GDC-0134 can be used for the study of amyotrophic lateral sclerosis (ALS)[1].

Applications: Neuroscience-Neurodegeneration

Formula: C19H20F4N6O2

References: [1]Jonathan S Katz, et al. A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS. Ann Clin Transl Neurol. 2022 Jan;9(1):50-66.

CAS Number: 1637394-01-4

Molecular Weight: 440.39

Compound Purity: 99.18

Research Area: Neurological Disease

Target: JNK

• SKU: MEXHY-148629-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-148629-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK