GluN2A Allosteric modulator 1

Product Description: GluN2A Allosteric modulator 1 (Compound 11) is an orally active, BBB-penetrable and highly selective GluN2A negative allosteric modulator. GluN2A Allosteric modulator 1 has IC50 values of 0.042 μM and 13 μM for GluN2A and GluN2B, respectively. GluN2A Allosteric modulator 1 can be used for the research of nervous system diseases[1].

Applications: Neuroscience-Neuromodulation

Formula: C20H16ClF2N5O2

References: [1]Bischoff FP, et al. Design, Synthesis, and Characterization of GluN2A Negative Allosteric Modulators Suitable for In Vivo Exploration. J Med Chem. 2025 Feb 27;68(4):4672-4693.

Molecular Weight: 431.82

Research Area: Neurological Disease

Target: iGluR

• SKU: MEXHY-168494-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168494-0
• Package Unit: Get quote
• Quantity Unit: STK