GNE-140 (racemate), CAS 1802977-61-2

Product Description: GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potent lactate dehydrogenase A (LDHA) inhibitor[1][2].

Applications: Cancer-programmed cell death

Formula: C25H23ClN2O3S2

References: [1]Purkey HE, et al. Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. ACS Med Chem Lett. 2016 Aug 26;7(10):896-901./[2] Ždralević M, et al. Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism. J Biol Chem. 2018 Oct 12;293(41):15947-15961.

CAS Number: 1802977-61-2

Molecular Weight: 499.04

Compound Purity: 99.38

Research Area: Cancer

Solubility: DMSO : 20 mg/mL (ultrasonic)

Target: Lactate Dehydrogenase

• SKU: MEXHY-100742-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100742-25
• Package Unit: 25 mg
• Quantity Unit: STK