GNE-272, CAS 1936428-93-1

Product Description: GNE-272 is a potent and selective CBP/EP300 inhibitor with IC50 values of 0.02, 0.03 and 13 μM for CBP, EP300 and BRD4, respectively. GNE-272 is also a selective in vivo probe for CBP/EP300[1].

Applications: Cancer-Kinase/protease

Formula: C22H25FN6O2

References: [1]Crawford TD, et al. Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300. J Med Chem. 2016 Dec 8;59(23):10549-10563.

CAS Number: 1936428-93-1

Molecular Weight: 424.47

Compound Purity: 99.60

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Epigenetic Reader Domain;Histone Acetyltransferase

• SKU: MEXHY-100726-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100726-25
• Package Unit: 25 mg
• Quantity Unit: STK