GNF-1331, CAS 603101-22-0

Product Description: GNF-1331 (compound 19) is a potent, selective and orally bioavailable porcupine inhibitor (IC50=12 nM). GNF-1331 blocks Wnt ligand secretion and subsequent Wnt signaling activity, and induces significant antitumor effects in the mouse MMTV-WNT1 xenograft tumor model[1].

Formula: C20H20N6O2S2

References: [1]Dai Cheng, et al. "Discovery of pyridinyl acetamide derivatives as potent, selective, and orally bioavailable porcupine inhibitors." ACS medicinal chemistry letters 7.7 (2016): 676-680.

CAS Number: 603101-22-0

Molecular Weight: 440.54

Compound Purity: 99.84

Research Area: Cancer

Target: Porcupine;Wnt

• SKU: MEXHY-123334-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123334-1
• Package Unit: 1 mg
• Quantity Unit: STK