GSK-340, CAS 2222509-79-5

Product Description: GSK-340 is a BET inhibitor with high affinity and significant selectivity for BD2 from BRD4 with a pIC50 of 7.2. GSK-340 inhibits MCP-1 release in Lipopolysaccharide (HY-D1056) treated PBMCs and whole blood with the pIC50 of 7.4 and 6.0, respectively. GSK-340 has immunomodulatory activity[1].

Formula: C26H31N3O2

References: [1]Law RP, et al. Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain. J Med Chem. 2018 May 24;61(10):4317-4334.

CAS Number: 2222509-79-5

Molecular Weight: 417.54

Research Area: Inflammation/Immunology

Target: Epigenetic Reader Domain

• SKU: MEXHY-120245-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120245-0
• Package Unit: Get quote
• Quantity Unit: STK