GTx-027, CAS 928122-40-1

Product Description: GTx-027 is an orally active and non-steroidal selective androgen receptor modulator (SARM). GTx-027 shows androgen receptor (AR) transactivation effects with the EC50 of 1.8 nM. GTx-027 acts selectively increase muscle weight (anabolic) without affecting secondary sexual organs (androgenic). GTx-027 has the protential for the study of breast cancer and stress urinary incontinence (SUI)[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C18H14ClN3O3

References: [1]Suriyan Ponnusamy, et al. Tissue Selective Androgen Receptor Modulators (SARMs) Increase Pelvic Floor Muscle Mass in Ovariectomized Mice. J Cell Biochem. 2017 Mar;118(3):640-646./[2]Narayanan R, et al. Selective androgen receptor modulators (SARMs) negatively regulate triple-negative breast cancer growth and epithelial:mesenchymal stem cell signaling. PLoS One. 2014 Jul 29;9(7):e103202.

CAS Number: 928122-40-1

Molecular Weight: 355.78

Compound Purity: 99.61

Research Area: Cancer; Endocrinology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Androgen Receptor

• SKU: MEXHY-171048-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171048-25
• Package Unit: 25 mg
• Quantity Unit: STK