HDAC-IN-85

Product Description: HDAC-IN-85 (Compound 1) is a BBB-permeable HDAC inhibitor. HDAC-IN-85 has an inhibitory effect on brain tumor cell lines. HDAC-IN-85 can induce acetylation, leading to DNA double-strand breaks, and induce the ubiquitination of RAD51, disrupting the DNA repair process. HDAC-IN-85 can be used in the research of glioblastoma[1].

Formula: C24H27FN4O5

References: [1]Chen IC, et al. Repurposing Linezolid in Conjunction with Histone Deacetylase Inhibitor Access in the Realm of Glioblastoma Therapies. J Med Chem. 2025 Feb 13;68(3):2779-2803.

Molecular Weight: 470.49

Research Area: Cancer

Target: DNA/RNA Synthesis;HDAC;RAD51

• SKU: MEXHY-170907-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170907-0
• Package Unit: Get quote
• Quantity Unit: STK