Product Description: HDAC9-IN-1 (Compound 7g) is a potent HDAC9 inhibitor, with an IC50 of 40 nM. HDAC9-IN-1 significantly inhibits several human cancer cells, induces apoptosis, modulates caspase-related proteins as well as p38, and causes DNA damage[1].
Formula: C27H22N4O3S
References: [1]Hsu KC, et al. Synthesis and biological evaluation of ortho-phenyl phenylhydroxamic acids containing phenothiazine with improved selectivity for class IIa histone deacetylases. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2406025.
Molecular Weight: 482.55
Research Area: Cancer
Target: HDAC