Product Description: hDHODH-IN-17 (Compound 10) is a human dihydroorotate dehydrogenase (hDHODH) inhibitor, with an IC50 of 0.188 μM. hDHODH-IN-17 is in good agreement with the hDHODH activity pocket and interacted well with amino acid residues. hDHODH-IN-17 is the potential broad-spectrum antiviral agent[1].
Applications: COVID-19-anti-virus
Formula: C21H13FN2O3S
References: [1]Liu X, et, al. Discovery of a New Class of Thiazolidin-4-one-Based Inhibitors of Human Dihydroorotate Dehydrogenase: Biological Activity Evaluation, Molecular Docking, and Molecular Dynamics. ACS Omega. 2025 Mar 21;10(12):12393-12402.
Molecular Weight: 392.40
Research Area: Infection
Target: Dihydroorotate Dehydrogenase