Product Description: HIV-1 inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. HIV-1 inhibitor-81 exhibits certain antiviral activity, with an EC50 of 250 nM for HIV-1[1].
Applications: COVID-19-anti-virus
Formula: C32H44N2O8S
References: [1]Ghosh AK, et al. Potent HIV‑1 protease inhibitors containing oxabicyclo octanol-derived P2-ligands: Design, synthesis, and X‑ray structural studies of inhibitor-HIV-1 protease complexes. Bioorg Med Chem Lett. 2025 Jan 21;120:130109.
Molecular Weight: 616.77
Research Area: Infection
Target: HIV;HIV Protease