Hsp90-IN-38, CAS 3065556-04-6

Product Description: Hsp90-IN-38 (compound 20m) is a HSP90 (heat shock protein) inhibitor. Hsp90-IN-38 exhibits strong HSP90 binding affinity with a Kd of 87 nM. Hsp90-IN-38 inhibits ATPase with an IC50 of 0.13 μM. Hsp90-IN-38 inhibits HCT116, MCF-7, SKBr3, K562 and A549 cells with IC50s of 0.187, 0.072, 0.105, 0.403 and 031 μM, respectively[1].

Applications: Cancer-programmed cell death

Formula: C28H35N3O5

References: [1]Zhang C, et al. Design, Synthesis, and Biological Evaluation of Chiral-Proline Derivatives as Novel HSP90 Inhibitors. ACS Med Chem Lett. 2025 Jan 22;16(2):301-310.

CAS Number: 3065556-04-6

Molecular Weight: 493.59

Research Area: Cancer

Target: HSP;Na+/K+ ATPase

• SKU: MEXHY-170895-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170895-0
• Package Unit: Get quote
• Quantity Unit: STK