hTG2 inhibitor VA4, CAS 2088001-23-2

Product Description: hTG2 inhibitor VA4 (compound VA4) is an irreversible Type 2 transglutaminase (TG2) inhibitor. hTG2 inhibitor VA4 reacts exclusively at the TG2 transamidase site, inhibits both transamidase and GTP-binding activities[1].

Formula: C33H41N5O6S

References: [1]Kerr C, et al. Transamidase site-targeted agents alter the conformation of the transglutaminase cancer stem cell survival protein to reduce GTP binding activity and cancer stem cell survival. Oncogene. 2017 May 25;36(21):2981-2990.

CAS Number: 2088001-23-2

Molecular Weight: 635.77

Compound Purity: 99.66

Research Area: Cancer

Target: Glutaminase

• SKU: MEXHY-122709-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-122709-10
• Package Unit: 10 mg
• Quantity Unit: STK