Product Description: Imeglimin (EMD 387008) is an oral glucose-lowering agent. Imeglimin improves insulin sensitivity. Imeglimin also reduces reactive oxygen species (ROS) production, increases mitochondrial DNA and improves mitochondrial function[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C6H13N5
References: [1]Vial G, et al. Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrialfunction in liver of a high-fat, high-sucrose diet mice model. Diabetes. 2015 Jun;64(6):2254-64./[2]Detaille D, et al. Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration. Cell Death Discov. 2016 Jan 18;2:15072.
CAS Number: 775351-65-0
Molecular Weight: 155.20
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Mitochondrial Metabolism;Reactive Oxygen Species
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