IMR-1A (Standard), CAS 331862-41-0

Product Description: IMR-1A (Standard) is the analytical standard of IMR-1A. This product is intended for research and analytical applications. IMR-1A, a acid metabolite of IMR-1, is a Notch inhibitor with an IC50 of 0.5 μM. IMR-1A has a 50-fold increase in potency with respect to IMR-1. IMR-1 can metabolize in vivo to IMR-1A[1].

Formula: C13H11NO5S2

References: [1]Astudillo L et al. The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis. Cancer Res. 2016 Jun 15;76(12):3593-603.

CAS Number: 331862-41-0

Molecular Weight: 325.36

Research Area: Cancer

Target: Drug Metabolite;Notch;Reference Standards

• SKU: MEXHY-100431AR-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100431AR-10
• Package Unit: 10 mg
• Quantity Unit: STK