INS018 055, CAS 2828567-39-9

Product Description: INS018 055 (compound 112) is the orally active TNIK and MAP4K4 inhibitor with IC50 values of 12-120, 12-120 nM, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C27H30FN7O

References: [1]Aleksandrs Zavoronkovs, et al. Analogs for the treatment of disease. WO2022179528A1./[2]Ren F, et al. A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models. Nat Biotechnol. 2025 Jan;43(1):63-75.

CAS Number: 2828567-39-9

Molecular Weight: 487.57

Compound Purity: 99.96

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Cadherin;Interleukin Related;MAP4K;TGF-beta/Smad

• SKU: MEXHY-160623-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160623-10
• Package Unit: 10 mg
• Quantity Unit: STK