ITX3, CAS 347323-96-0

Product Description: ITX3 is a specific and nontoxic inhibitor of TrioN (N-terminal GEF domain of the multidomain Trio protein) with an IC50 value of 76 μM. ITX3 can be used for the research of agent[1][2].

Formula: C22H17N3OS

References: [1]Bouquier N, et al. A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathway. Chem Biol. 2009 Jun 26;16(6):657-66./[2]Yano T, et al. Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling. J Cell Biol. 2011 Apr 18;193(2):319-32.

CAS Number: 347323-96-0

Molecular Weight: 371.45

Compound Purity: 98.60

Research Area: Others

Solubility: DMSO : 2 mg/mL (ultrasonic;warming;heat to 80°C)

Target: ROCK

• SKU: MEXHY-16663-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-16663-25
• Package Unit: 25 mg
• Quantity Unit: STK