JNJ-47965567, CAS 1428327-31-4

Product Description: JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology[1].

Applications: Neuroscience-Neuromodulation

Formula: C28H32N4O2S

References: [1]Bhattacharya A, et al. Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567. Br J Pharmacol. 2013 Oct;170(3):624-40.

CAS Number: 1428327-31-4

Molecular Weight: 488.64

Compound Purity: 99.79

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: P2X Receptor

• SKU: MEXHY-101418-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101418-100
• Package Unit: 100 mg
• Quantity Unit: STK