Product Description: JNJ-9676 is an orally active inhibitor of membrane (M) protein. JNJ-9676 has in vitro antiviral activity against SARS-CoV-2, SARS-CoV, and sarbecovirus from bats and pangolins. JNJ-9676 inhibits viral assembly by stabilizing the conformational changes of the M protein dimer, preventing the release of infectious viruses. JNJ-9676 has significant antiviral effects and can be used in research on the prevention and treatment of coronavirus infections[1].
Formula: C28H21F2N5O2
References: [1]Van Damme E, et al. A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein. Nature. 2025 Apr;640(8058):506-513.
CAS Number: 3026520-19-1
Molecular Weight: 497.50
Research Area: Infection
Target: DNA/RNA Synthesis;SARS-CoV