JPHM-2-167, CAS 1258877-17-6

Product Description: JPHM-2-167 (Compound 11) is a selective PHD (prolyl hydroxylase domain enzyme) inhibitor. JPHM-2-167 inhibits PHD2, PHD3 with IC50s of 0.253 μM and 3.95 μM, respectively. JPHM-2-167 can be used for chronic kidney disease [1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C30H28N6O2

References: [1]Xu J, et al. Discovery of Novel and Potent Prolyl Hydroxylase Domain-Containing Protein (PHD) Inhibitors for The Treatment of Anemia. J Med Chem. 2024 Jan 25;67(2):1393-1405.

CAS Number: 1258877-17-6

Molecular Weight: 504.58

Research Area: Metabolic Disease

Target: HIF/HIF Prolyl-Hydroxylase

• SKU: MEXHY-170914-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170914-0
• Package Unit: Get quote
• Quantity Unit: STK