JR5-26B, CAS 2446965-04-2

Product Description: JR5-26B is an orally active apoptosis inducer. JR5-26B induces cell death through copper-mediated apoptosis and necroptosis. JR5-26B exhibits antiproliferative activity on MIA PaCa-2, PANC-1, PAN02, SU.86.86, and KPC-2 cells with IC50s of 0.6, 4.4, 8.0, 1.1, and 3.4μM, respectively[1].

Formula: C19H17FN6O

References: [1]Roy J, et al. Copper-KRAS-COX2 Axis: A Therapeutic Vulnerability in Pancreatic Cancer. J Med Chem. 2025 Apr 24;68(8):8400-8428.

CAS Number: 2446965-04-2

Molecular Weight: 364.38

Research Area: Cancer

Target: Apoptosis

• SKU: MEXHY-173477-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173477-0
• Package Unit: Get quote
• Quantity Unit: STK