Jun13296, CAS 3063566-68-4

Product Description: Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13  µM, Ki  = 8.8  nM). Jun13296 exhibits potent inhibition against SARS-CoV-2 variants and Nirmatrelvir (HY-138687)-resistant mutants. Jun13296 improves lung viral titers, and prevents lung tissue damage in a SARS-CoV-2 infection model[1].

Formula: C30H34N6O

References: [1]Jadhav P, et al. Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates. Nat Commun. 2025 Feb 13;16(1):1604.

CAS Number: 3063566-68-4

Molecular Weight: 494.63

Target: SARS-CoV;Virus Protease

• SKU: MEXHY-168916-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168916-0
• Package Unit: Get quote
• Quantity Unit: STK