K-604 (dihydrochloride) (Standard), CAS 217094-32-1

K-604 (dihydrochloride) (Standard), CAS 217094-32-1
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MEXHY-100400AR-0
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MedChemExpress

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Product Description: K-604 (dihydrochloride) (Standard) is the analytical standard of K-604 (dihydrochloride). This product is intended for research and analytical applications. K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC50 of 0.45±0.06 μM.

Formula: C23H32Cl2N6OS3

References: [1]Ikenoya M, et al. A selective ACAT-1 inhibitor, K-604, suppresses fatty streak lesions in fat-fed hamsters without affecting plasma cholesterol levels. Atherosclerosis. 2007 Apr;191(2):290-7./[2]Shibuya Y, et al. Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage. Neurobiol Aging. 2015 Jul;36(7):2248-2259.

CAS Number: 217094-32-1

Molecular Weight: 575.64

Research Area: Cardiovascular Disease

Target: Acyltransferase;Reference Standards
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SKU MEXHY-100400AR-0
Manufacturer MedChemExpress
Manufacturer SKU HY-100400AR-0
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